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Can too much minEPAP cause nervousness/shakiness in morning?
Since I was having some issues with my SpO2 dropping below 90%, I increased minEPAP from 5.00, to 5.40. Also using PS3, and BIPAP goes from 5.40 to 8.40 on breathes I think.

The last few days, I've still been feeling really tired, and upon waking, feel very jittery and nervous, like I'm going to have an anxiety/panic attack.
I haven't felt this way in a very long time, but it has happened in the past when I started CPAP last year.

Last night I kept waking up, not sure why, but i didnt sleep well and had trouble going back to sleep. Tried taking Melatonin and also Clonopin that my doctor prescribed. Flow limitation looks good. I know I have major leaks, but that never caused this type of nervous feeling in the past. And usually my O2 is better with the more leaks I have.

ResMed AirCurve 10 vAuto
Pressure EPAP min 5.6, IPAP Max 16, PS 3.

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Your EPAP is about as low as it goes. Your problem is leaks and therapy fragmentation. I would look at anxiety as a primary problem, and not a product of PAP therapy.
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Fragmented sleep and low O2 will not help, but lack of sleep and worry will not help.
Stop worrying and get a good sleep, do you the world of good.
Do you get any pops or noises in the head when you just get up by any chance?
I am NOT a doctor.  I try to help, but do not take what I say as medical advice.

I am just a long term user of c.p.a.p. and therefore I have some experience in using these machines and equipment.

However, I am NOT an expert, so advice given should be taken as given in good faith only and NOT medical advice.

Every journey, however large or small starts with the first step.   Coffee
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No pops or noises. Just have palpitations and heart beats fast at times and when I sit up feel like my blood pressure is a little low. But every time they check blood pressure during the day they say it is fine.
ResMed AirCurve 10 vAuto
Pressure EPAP min 5.6, IPAP Max 16, PS 3.

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