Of course - but I figured if you were a linux/BSD/xNIX user you would already have had a go at wine.
... unless of course you use something _really_ obscure???
I am continually surprised at the programs people get to run in wine. I have only tinkered to see how it worked. IIRC wine is also ported to the current MacOS. I stick with windows though and use VMware to support an Ubuntu partition for the little bit stuff I do with Linux. The reverse also is commonly done with VMWare or similar making a windows partition on the xNix machine..
I started with Mini-computers in the 70's... PDP-8 and a little heard of General Automation SPC16/40