After using the machine for a while (been on one for 6 yrs now) I ran out of distilled water and started to use boiled water and that worked fine but as soon as I got lazy, used tap water and didn't clean the machine for a week, I had...the slime build up. So Clean Often and use Distilled Water IMHO. However if you have a heated system and the tank has a warmer plate make sure that the surface has not lost it's coating which will make it really quite not nice. The only way to solve that issue is to replace the tank. ( I have an old brick like machine so you may not have these issues)
Just a little experience talking.
I dump mine before going to bed, rinse it out, give it a shake, dump, and refill with water from the tap. Every once in a while, I soak it in a vinegar solution but that's it. I am very lazy.
In the winter, all of the water is gone by morning anyway (and I get rudely awakened by that gawd awful burnt smell).
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