Perhaps an oral antihistamine?
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HPA Lanolin cream helps if using nasal pillows but as "JeremiahOSB" using full face mask and the irritation around the edge of the nostril, might be the cushion wrong size and rubbing on the nostrils. Try different size cushion or different mask
I started using a FFM about a month ago and found it to be very itchy either inside the nose or around the lips.
I do have to take my mask off a few times to scratch.
WELCOME! to the forum.!
Could be that your itchy nose will settle down as you get used to the mask and machine.
Hang in there for more responses to your post and best of luck to you with your CPAP therapy.
-I have found that normally I can condition myself to ignore slight itchiness long enough for it to go away. Last night, however, I got an itch just under my nose that was so persistent and insistent that I finally had to shut the machine down, take my mask off and scratch it. What a pain but it sure felt good. It did not bother me at all after that.