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Lymphocytosis in Patients with Obstructive Sleep Apnea
#1
Hi all.

I have moderate to severe sleep apnea.

Since before the diagnosis, I have had numerous blood tests (since winter 2014) that have revealed a slighter higher than average lymphocyte count. Now, every year I see a blood specialist who examines my blood and ultrasound results. He thinks I may have a reaction to something. 

An article I just read would seem to indicate a link between severe apnea and Lymphocytosis.

Here it is: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023772/

The important bit of info for us is: "lymphocytic inflammation is present in the pharyngeal muocsa in OSA".

Just curious, but how many others out there have experienced this?
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#2
Interesting article, however I think these are untreated OSA patients being compared with a healthy non-OSA cohort. It would seem a treated OSA patient using CPAP that has an effective AHI < 5 should not exhibit the pharyngeal irritation of an untreated individual, so the condition should be mitigated by effective CPAP. That aspect of the study is yet to be evaluated, but it seems a reasonable hypothesis that effective treatment of OSA by CPAP should mitigate any OSA related Lymphocytosis.
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#3
That's the problem with many of these articles. They need to stress harder that the results of XZ study were from people with *untreated* OSA.

Meanwhile, the article says it is unknown if the inflammation is causes the laryngeal collapse or if the collapse causes the inflammation although animal testing says it is the latter.

It is interesting that you got the diagnosis after you started CPAP, not before. If you didn't have any symptoms prior, then I would assume it is something other than OSA unless it is not being adequately controlled. Just keep in mind I am not a doctor nor do I play one on the internet.
PaulaO2
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