I was in Korea last week with my ResMed AirSense 10 AutoSet. I slide it into a gallon zip lock bag so the TSA doesn't manhandle it and stuff it into my roll-aboard. What I changed when packing is to omit my shaving kit and put that stuff in the side pockets of my roll-aboard. I have no problem packing for a week if I pack carefully.
I have my real machine with humidifier and ClimateLine heated hose. If I had to lug it 10 miles in a backpack with lithium batteries or do a long motorcycle trip with it where space was extremely limited, I might reconsider. For business travel, I think an A10 is compact enough.