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[News] Study: Women with sleep apnea have higher degree of brain damage than men
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SuperSleeper Offline

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Post: #1
Study: Women with sleep apnea have higher degree of brain damage than men
Okay, before you crucify me, remember I'm just posting the article... don't shoot the messenger, please! Bigwink

Women with sleep apnea have higher degree of brain damage than men, UCLA study shows


Women suffering from sleep apnea have, on the whole, a higher degree of brain damage than men with the disorder, according to a first-of-its-kind study conducted by researchers at the UCLA School of Nursing. The findings are reported in the December issue of the peer-reviewed journal SLEEP.

Obstructive sleep apnea is a serious disorder that occurs when a person's breathing is repeatedly interrupted during sleep, sometimes hundreds of times. Each time, the oxygen level in the blood drops, eventually resulting in damage to many cells in the body. If left untreated, it can lead to high blood pressure, stroke, heart failure, diabetes, depression and other serious health problems.

Approximately 10 years ago, this UCLA research team was the first to show that men with obstructive sleep apnea have damage to their brain cells.

For this latest, multi-year study, "Sex Differences in White Matter Alterations Accompanying Obstructive Sleep Apnea," the researchers looked at patients who were diagnosed with obstructive sleep apnea at the UCLA Sleep Laboratory. They compared the nerve fibers in these patients' brains — known as white matter — to fibers of individuals without sleep problems and focused on unearthing the difference in brain damage between men and women with sleep apnea.

"While there are a great many brain studies done on sleep apnea and the impact on one's health, they have typically focused on men or combined groups of men and women, but we know that obstructive sleep apnea affects women very differently than men," said chief investigator Paul Macey, assistant professor and associate dean of information technology and innovations at the UCLA School of Nursing. "This study revealed that, in fact, women are more affected by sleep apnea than are men and that women with obstructive sleep apnea have more severe brain damage than men suffering from a similar condition."

In particular, the study found that women were impacted in the cingulum bundle and the anterior cingulate cortex, areas in the front of the brain involved in decision-making and mood regulation. The women with sleep apnea also showed higher levels of depression and anxiety symptoms, the researchers said.

"This tells us that doctors should consider that the sleep disorder may be more problematic and therefore need earlier treatment in women than men," Macey said.

With this finding as a foundation, Macey said that the next step is for researchers to "untangle the timing of the brain changes" and find out if treating sleep apnea can help the brain.

"What we don't yet know," he said, "is, did sleep apnea cause the brain damage, did the brain damage lead to the sleep disorders, or do the common comorbidities, such as depression, dementia or cardiovascular issues, cause the brain damage, which in turn leads to sleep apnea."



fair use applies:
http://www.eurekalert.org/pub_releases/2012-12/uoc--wws120312.php

SuperSleeper
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12-03-2012 10:46 PM
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zonk Offline

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Post: #2
RE: Study: Women with sleep apnea have higher degree of brain damage than men
according to a Swedish study:
Fully half of the 400 women given overnight sleep tests in a new Swedish study turned out to have mild-to-severe sleep apnea.
http://www.reuters.com/article/2012/09/0...A420120907
12-03-2012 11:07 PM
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