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Please help - still completely fatigued
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PhyllisBalboa Offline

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Posts: 155
Joined: May 2014

Machine: ResMed VPAP Adapt S9 (36067), ASV mode
Mask Type: Nasal pillows
Mask Make & Model: Swift FX for Her
Humidifier: H5i
CPAP Pressure: EPAP: 4.4; PS: 1-6
CPAP Software: SleepyHead

Other Comments: diabetes type 1, fibromyalgia, MTHFR double genetic mutation

Sex: Female
Location: American in Montreal, Qc

Post: #31
RE: Please help - still completely fatigued
(10-31-2014 02:34 PM)justMongo Wrote:  Looks like 23andMe is not doing tests right now... some problem with the FDA.

My understanding is that they're not allowed to give you any medical info about what your tests might mean for your future, but can still report the raw data, which includes the SNP name and its status as normal or mutated on one or both genes (you get one from each parent). We've always been encouraged to run the raw data through a third party for the categorization and interpretation. Usually costs $25 or so. But you can look up the SNPs that are mutated and see what that means. Lots of info on the internet about DNA, genes and SNPs.

The FDA decided that maybe people would get unnecessary surgery or worry too much if they knew their genetic status. You know how that goes.

Rolleyes
10-31-2014 02:52 PM
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Jay Aitchsee Offline

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Posts: 5
Joined: Aug 2014

Machine: ResMed S9
Mask Type: Full face mask
Mask Make & Model: Simplus
Humidifier: H5i
CPAP Pressure: 9-11
CPAP Software: ResScan SleepyHead

Other Comments: CPAP since 2008

Sex: Male
Location: Southwest Florida

Post: #32
RE: Please help - still completely fatigued
(10-31-2014 08:29 AM)marxxx Wrote:  Thanks for ideas guys.
Mongo - I am going to request a cardiac work up at my dr appt next week. I don't expect that to be root cause of the problem, but that's what the Dr's are for.


Phyllis - My B levels are good. I have actually improved several deficiencies over the course of the year. There may be more but B & D are both good.

I should probably start a separate thread for this, most of my apneas seem to occur while in REM.

As a couple others have noted, I think the full cardio work-up is a good idea. In my own case, I found a known blockage had increased from 75% to 80+% (over 17 yrs), had it stented, and there was a noticeable decrease in fatigue, though fragmented sleep did not improve.
As to D3, many now consider optimal to be higher than the "normal" low of 30ng/ml. The Vitamin D council recommends around 60. (you'll have to Google it, I can't yet provide links)

Jay
11-12-2014 08:29 AM
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DariaVader Offline
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Posts: 1,827
Joined: Nov 2014

Machine: Resmed S9 AutoSet
Mask Type: Nasal pillows
Mask Make & Model: Airfit P10 for Her
Humidifier: H5i humidifier with ClimateLine heated hose
CPAP Pressure: 8-15
CPAP Software: SleepyHead

Other Comments: diabetes II, Thyroidectomized, Primary Immune Deficiency, and the list goes on :P

Sex: Female
Location: Oregon

Post: #33
RE: Please help - still completely fatigued
(10-31-2014 02:52 PM)PhyllisBalboa Wrote:  
(10-31-2014 02:34 PM)justMongo Wrote:  Looks like 23andMe is not doing tests right now... some problem with the FDA.

My understanding is that they're not allowed to give you any medical info about what your tests might mean for your future, but can still report the raw data, which includes the SNP name and its status as normal or mutated on one or both genes (you get one from each parent). We've always been encouraged to run the raw data through a third party for the categorization and interpretation. Usually costs $25 or so. But you can look up the SNPs that are mutated and see what that means. Lots of info on the internet about DNA, genes and SNPs.

The FDA decided that maybe people would get unnecessary surgery or worry too much if they knew their genetic status. You know how that goes.

Rolleyes

There is a great free (accepting donations) tool called Promethease which will give you a lot of the health info if you had a test at 23andme and download your raw data.
12-21-2014 06:00 PM
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quiescence at last Offline

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Posts: 753
Joined: Nov 2014

Machine: REMstar System One with Autoflex
Mask Type: Full face mask
Mask Make & Model: Quattro AirFit F10
Humidifier: yes typical setting = 4
CPAP Pressure: 5-13 Autotritrating CPAP
CPAP Software: SleepyHead EncoreBasic

Other Comments: CMS-50F Plus oximeter /w SPO2 Assistant software. Avowed mouth-breather switching to nose-breathing

Sex: Male
Location: US

Post: #34
RE: Please help - still completely fatigued
my original sleep study indicated OAs and Hs, but no CAs. the study did not indicate any info with regard to NREM and REM sleep. it was a home test, and doc says you cannot tell this in the home study I took.

story continues, I got APAP setting 4-20 cm. I got CAs along with the OAs and Hs right off the bat, even at relatively low pressures (4-7 cm). doc says best interp they have right now is that it is possibly "treatment emergent central apneas." since I have just begun, I anticipate these will trail off.

I have leakage out the cheeks using my FFM as well, but none that the machine characterizes as large leaks. I did want to suggest your leakage might be interfering with the detection of events. Are your leaks still happening, and if they are fixed, did your AHI go up or down.

Good luck and see PM.

Dedicated to QALity sleep.
You'll note I am listed as an Advisory Member. I am honored to be listed as such. See the fine print - Advisory Members as a group provide advice and suggestions to Apnea Board administrators and staff concerning Apnea Board operation and administrative policies. Membership in the Advisory Member group should not be understood as in any way implying medical expertise or qualification for advising Sleep Apnea patients concerning their treatment.
12-22-2014 01:00 AM
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