Hello Guest, Welcome to Apnea Board !
As a guest, you are limited to certain areas of the board and there are some features you can't use.
To post a message, you must create a free account using a valid email address.

or Create an Account

New Posts   Today's Posts

Question on Resmed vs. Respironics APAP for Complex / Mixed Apnea
RE: Question on Resmed vs. Respironics APAP for Complex / Mixed Apnea
Thanks, RayBee and Sleepless -- I appreciate your posts.

Obviously, that SERV-HF study was for patients with diagnosed heart failure. I also noticed in the study that the outcomes were worse in patients with the worst heart failure (lowest ejection fraction). So I don't mean to automatically suggest that the study should raise concerns for those without heart failure.

At the same time, I did notice that the ASV patients had what we would normally think of as improvement in their situations -- better oxygenation, much lower AHIs and AIs, and even less daytime sleepiness -- yet had worse survival with somewhat greater overall mortality and cardiac mortality specifically. (At the same time, I don't believe they had actual improvements in "Qualify of Life," notwithstanding the reduced sleepiness.) So that gave me pause, and I wondered if it's possible that some of the same lessons might apply to those who don't have heart failure: that improvement in oxygenation and AHI and sleepiness don't necessarily translate into better long-term outcomes.

As far as the actual pressure ranges, I understand your (RayBee's) point and did click on the thumbnail you attached showing the 25 cm maximum (though also noting Sheepless' comments about what might happen in actuality). I guess my point was less about the exact numerical pressure than a concern that ASV, by raising intrathoracic (intra-chest) pressure during inspiration, reverses an aspect of the normal physiology (lower pressure during inspiration, higher during expiration), which could also alter some of the normal changes of cardiac output that happen during the respiratory cycle (inspiration + respiration).

As you can tell, I'm both detail oriented and a worrier (not an easy combination, I can assure you, to live with) who is always seeing the limitations of our our current knowledge and feeling the need to get to the bottom of things. The problem is, it's often just not possible to know, given the current state of knowledge, what the best path really is.

Once again, I much appreciate the support and helpful comments and suggestions I've been receiving here.
Post Reply Post Reply

Donate to Apnea Board  

Possibly Related Threads...
Thread Author Replies Views Last Post
  [Pressure] Help Calibrating APAP Pressure TheWallofsleep 6 198 Yesterday, 05:55 PM
Last Post: Gideon
  Oscar Data ?/ switch from APAP to Resmed Bipap or ASV? Shulamet 14 324 04-20-2021, 06:48 PM
Last Post: SarcasticDave94
  New APAP user - OSCAR report help! ravp 3 157 04-20-2021, 09:18 AM
Last Post: ravp
Idea [Treatment] ASV settings for treatment of complex sleep apnea JoeyWallaby 223 9,779 04-18-2021, 10:30 AM
Last Post: Geer1
  Question about non-Resmed FF masks StevesSp 3 99 04-17-2021, 05:50 PM
Last Post: Crimson Nape
  New APAP user, worried about centrals mollyjz 19 453 04-16-2021, 10:25 PM
Last Post: SarcasticDave94
  Looking to optimize my APAP usage w/Oscar and sleep study info BionicSpud 13 454 04-10-2021, 11:47 AM
Last Post: Gideon

New Posts   Today's Posts

About Apnea Board

Apnea Board is an educational web site designed to empower Sleep Apnea patients.