Post Reply 
Theophylline for Periodic Breathing
Author Message
richb Offline

Advisory Members

Posts: 534
Joined: Jun 2015

Machine: Resmed AirCurve 10 ASV
Mask Type: Nasal mask
Mask Make & Model: ResMed Mirage FX
Humidifier: Built in
CPAP Pressure: Epap 6 Ipap 8 Auto ASV
CPAP Software: ResScan SleepyHead

Other Comments: Idiopathic Central Apnea

Sex: Male
Location: Vermont

Post: #1
Theophylline for Periodic Breathing
I am currently on Auto Bi-Pap with PS of 4 Max IPAP 16. The machine is generally running with a high of about 12. I am experiencing numerous (in the hundreds) of Cheyne Stokes breathing episodes that did not appear in my sleep study. My sleep study did show almost entirely Hypopneas giving an AHI of 44. No Centrals or Cheyne Stokes breathing. I believe that my Sleep study Hypos were actually Periodic breathing. My machine has converted the Hypos to Cheyne Stokes breathing through the mechanism of CO2 washout. I am going to be working with the DR and Techs to resolve the issue. My concern is that I don't want to fix what wasn't broken in the first place. In other words I think that I need to be treating the Hypos as Periodic Breathing episodes. So farXPAP has only made things worse. I have read that Theophylline has been used to control Periodic Breathing. Has anyone had any experience with this?
06-24-2015 04:48 PM
Find all posts by this user Post Reply Quote this message in a reply

Donate to Apnea Board
eseedhouse Online

Advisory Members

Posts: 881
Joined: Dec 2014

Machine: ResMed Airsense 10 Autoset
Mask Type: Full face mask
Mask Make & Model: SimPlus
Humidifier: ResMed
CPAP Pressure: 7-10
CPAP Software: SleepyHead

Other Comments: Also on supplemental O2 at 3L/min. while sleeping.

Sex: Male
Location: Victoria, British Columbia

Post: #2
RE: Theophylline for Periodic Breathing
Theophylline is a stimulant, so it's hard to see how it will help you sleep better. But I am no doctor.

Ed Seedhouse
VA7SDH

I am neither a Doctor, nor any other kind of medical professional.

Actually you know, it is what it isn't.
06-24-2015 05:28 PM
Find all posts by this user Post Reply Quote this message in a reply
richb Offline

Advisory Members

Posts: 534
Joined: Jun 2015

Machine: Resmed AirCurve 10 ASV
Mask Type: Nasal mask
Mask Make & Model: ResMed Mirage FX
Humidifier: Built in
CPAP Pressure: Epap 6 Ipap 8 Auto ASV
CPAP Software: ResScan SleepyHead

Other Comments: Idiopathic Central Apnea

Sex: Male
Location: Vermont

Post: #3
RE: Theophylline for Periodic Breathing
(06-24-2015 05:28 PM)eseedhouse Wrote:  Theophylline is a stimulant, so it's hard to see how it will help you sleep better. But I am no doctor.

Theophyllin is one of the 2 or 3 drugs used to treat this disorder. http://www.ncbi.nlm.nih.gov/pubmed/14642143
06-24-2015 05:57 PM
Find all posts by this user Post Reply Quote this message in a reply

Donate to Apnea Board
richb Offline

Advisory Members

Posts: 534
Joined: Jun 2015

Machine: Resmed AirCurve 10 ASV
Mask Type: Nasal mask
Mask Make & Model: ResMed Mirage FX
Humidifier: Built in
CPAP Pressure: Epap 6 Ipap 8 Auto ASV
CPAP Software: ResScan SleepyHead

Other Comments: Idiopathic Central Apnea

Sex: Male
Location: Vermont

Post: #4
RE: Theophylline for Periodic Breathing
(06-24-2015 05:57 PM)richb Wrote:  Theophyllin is one of the 2 or 3 drugs used to treat this disorder. http://www.ncbi.nlm.nih.gov/pubmed/14642143

It looks like the drug acetazolamide is the drug of choice to treat CA and Periodic Breathing. It is the preferred drug for High Altitude Sickness which produces CAs in a manor similar to Periodic Breathing caused by a disrupted CO2 controller system. CO2 washout can aggravate already existing Periodic Breathing or even cause Periodic Breathing when CPAP pressures and Pressure differentials are set too high.
07-01-2015 03:32 PM
Find all posts by this user Post Reply Quote this message in a reply
richb Offline

Advisory Members

Posts: 534
Joined: Jun 2015

Machine: Resmed AirCurve 10 ASV
Mask Type: Nasal mask
Mask Make & Model: ResMed Mirage FX
Humidifier: Built in
CPAP Pressure: Epap 6 Ipap 8 Auto ASV
CPAP Software: ResScan SleepyHead

Other Comments: Idiopathic Central Apnea

Sex: Male
Location: Vermont

Post: #5
RE: Theophylline for Periodic Breathing
[attachment=1569][attachment=1568][/quote]

It looks like the drug acetazolamide is the drug of choice to treat CA and Periodic Breathing. It is the preferred drug for High Altitude Sickness which produces CAs in a manor similar to Periodic Breathing caused by a disrupted CO2 controller system. CO2 washout can aggravate already existing Periodic Breathing or even cause Periodic Breathing when CPAP pressures and Pressure differentials are set too high.
[/quote]

Here are examples of Periodic Breathing and Periodic Breathing with CAs.
07-01-2015 03:52 PM
Find all posts by this user Post Reply Quote this message in a reply

Donate to Apnea Board
Post Reply 


Possibly Related Threads...
Thread: Author Replies: Views: Last Post
  Classic example of Sleep-Wake-Junk breathing robysue 4 207 Yesterday 09:51 PM
Last Post: richb
  Soft cervical collar: a tip for mouth breathing and chin tucking Visitor 44 3,656 Yesterday 11:43 AM
Last Post: PaytonA
  Bite Guard for Mouth Breathing mcsheltie 11 503 11-29-2016 11:46 AM
Last Post: mcsheltie
  Mouth Breathing mcsheltie 31 1,047 11-15-2016 08:25 PM
Last Post: chill
  Not mouth breathing but air leaking between lips Roy289 20 672 11-11-2016 07:19 PM
Last Post: Sleeprider
  Chinstrap doesn't prevent mouth breathing, how to solve? Snurkel 21 2,082 10-03-2016 05:03 PM
Last Post: Roy289
Question [Symptoms] Fake or real OA - back sleep and diaphragm breathing jm54 1 280 09-15-2016 07:46 PM
Last Post: chill

Forum Jump:

Who's Online (Complete List)