Traveling with the CPAP was no problem. It was obvious security people see a lot of machines as mine didn't get a second look except I had to open the case when we came BACK into the country in Seattle. And no one questioned me having the CPAP and a regular carry on bag.
The machine functioned perfectly on 220 volts -- all I needed was a plug adapter, the RemStar power supply automatically shifted to the higher voltage (almost every electrical appliance made today does).
Turned out I didn't have to use the humidifier at all as the humidity was pretty high throughout the trip (being on a boat). At home the humidifier is a must.
The 10-hour time difference causes some fairly serious jet lag but I felt the CPAP made it easier to sleep. In addition it made it easier to breath at night when I came down with a cold midway through the trip.
When I started CPAP in June I planned to leave it home for the trip because I thought taking it would be a hassle. But when the time came I decided I wouldn't be comfortable without it and, in fact, I think it actually made the trip more enjoyable.
Just thought some other newbys out there might get some info from my experience,