About 8 ounces is good, through the combination of both nostrils. Mostly let it THROUGH and spit it out. You want it to OPEN the passage through.
Good enough: a simple cup you sip by placing it OVER your upper lip and sipping THROUGH YOUR NOSE instead of your mouth. You don't NEED any special 'neti pots' or the stuff below.
Better: Special little squirt bottom (fill tube goes to bottom for squirting UP) by NeilMed
Best: NeilMed SinuGator -- not much more expensive that the silly little bottle above but works best of all the methods I have tried.
BTW: Neti pots are STUPID unless you are a new age hippy and just want your sinus irrigation to sound cool.
Sleep study AHI: 49 RDI: 60 -- APAP 10-11 w/AHI: 1.5 avg for 7-days (up due likely to hip replacement recovery)
"We can all breathe together or we will all suffocate alone."