As aside:
first, I found one root cause of problems is that I have been removing my partial lower frontal dental plate (bout of oral cancer) every night, which allowed my mouth front to partially collapse so lip(s) most times fell outside mask edge (insuring BIG leaks % snores etc). As an experiment I left the plate in overnight and slept through night 7-8 hours and score hovered consistently around 4-5. My dentist is working on a bridge much like football jocks use, that pushes out lower front jaw skin (like if I had all my teeth and gum there) insuring lips stay inside mask.
Second I reduced my pressure to 6.0 straight CPAP no Cflex or AFlex. Now getting 6-7 hours sleep with AHI of 4-5. Granted this may not be best solution but sure beats 2-3hours of tortured interrupted sleep of mask pharts, squeals and air in eyes etc, with straps headache tight. And I have gone thorough about $500 different masks and right now the resmed foam edge air touch seems to work at the low pressure and slightly tight straps, but at the prescribed 16 pressure with or without AFex or CFles options, problems return. Once I get consistent readings I plan to jump pressure to 8 and see results. When I reach the pharts/squeal/ eye air stages I will back off one full notch.
Best solution I can think of short of throwing CPAP machine into garbage (along with quack that came up with this idea, but that's my opinion, your mileage may vary as they say).