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PAP Technology

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Overview of device types CPAP maintains a continuous Positive Airway Pressure (PAP) throughout inspiration and expiration. Autoadjusting (Auto) CPAP can gradually increase or decrease the pressure based on respiratory events, but similarly maintains the same pressure throughout the respiratory cycle. This can be helpful for patients who may need a higher pressure in rapid eye movement (REM) or supine position, but cannot tolerate the higher pressure through the entire night. AutoCPAP can also be used diagnostically to determine a fixed pressure setting.

Most CPAP devices allow for pressure settings between 4 and 20 (all pressures in cm⋅H2O). An EPAP of 4 is the lowest pressure needed to provide enough flow to clear the dead space from the device, tubing, and airway to prevent rebreathing of exhaled air. The goal of CPAP is to increase upper airway pressure enough to provide a pneumatic splint to open the airway, which may collapse during inspiration. Typically, the pressure is set to prevent hypopnea, apnea, snoring, flow limitation, and arousals. By providing positive end expiratory pressure, CPAP may recruit alveoli and improve ventilation.

BiPAP provides a higher pressure during inspiration and lower pressure during expiration. This may improve tolerance and help with ventilation. A backup rate can be added to give a breath with weak or absent respiratory effort. AutoBiPAP may adjust either the expiratory positive airway pressure (EPAP) and inspiratory positive airway pressure (IPAP) with a fixed pressure support (PS) or may adjust them independently.

SV is a bilevel system that continuously changes the inspiratory PS on a breath-by-breath basis in order to achieve a target ventilation or flow for a more constant breathing pattern, especially in the treatment of periodic breathing or Cheyne–Stokes respiration (CSR). Auto forms of SV also increase EPAP in response to obstruction.

Volume-assured pressure support (VAPS) is a variable bilevel PAP that allows the target volume or ventilation to be programmed, which allows more control of ventilation. This is useful for patients with combined periodic breathing and hypoventilation or patients with REM-related hypoventilation related to conditions like chronic obstructive pulmonary disease (COPD), neuromuscular disorders, or obesity, who may need different PS levels at different times.



Table 1 ResMed’s logic for phase determination

Flow Rate of change Phase
Zero Increasing Start inspiration
Small positive Increasing slowly Early inspiration
Large positive Steady Peak inspiration
Small positive Decreasing slowly Late inspiration
Zero Decreasing fast Start expiration
Small negative Decreasing slowly Early expiration
Large negative Steady Peak expiration
Small negative Increasing slowly Late expiration
Zero Steady Expiratory phase



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