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CPAP Algorithms

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ResMed

AutoSet

AutoSet for Her

AutoSet for Her mode is based on key aspects of ResMed’s AutoSet algorithm and delivers therapeutic responses tailored to the characteristics of female OSA patients.

The AutoSet for Her is similar to ResMed’s AutoSet algorithm with the following modifications:

  • Reduced rate of pressure increments designed to help prevent arousals.
  • Slower pressure decays.
  • Treats apneas up to 12 cm H2O and continues to respond to flow limitation and snore up to 20 cm H2O.
  • Minimum pressure (Min. Pressure) that adjusts according to the frequency of apneas:
    • If two apneas occur within a minute, the pressure reached in response to the second apnea will become the new minimum treatment pressure until the next treatment session.

For Her Pressure.png

Patients who use AutoSet for Her will still get the benefits of ResMed's AutoSet technology including improved sensitivity to flow-limitation and Central Sleep Apnoea Detection with ForcedOscillation Technique.

Algorithms - AutoSet for Her

The pioneering new algorithm in the AirSense™ 10 AutoSet for Her is based on ResMed’s proven AutoSet algorithm and delivers therapeutic responses that have been tailored to the characteristics of obstructive sleep apnea (OSA) in women.

Research has shown that women with OSA have more upper airway resistance and flow limitation than the general OSA population1, which is why the AutoSet for Her algorithm has been designed to be more sensitive to flow limitation.

In addition, the algorithm provides more subtle changes in therapy pressure to minimize sleep disturbance. The AutoSet for Her algorithm also automatically adjusts the minimum AutoSet pressure if multiple apneas are occurring below a certain threshold.

AutoSet for her.png


Algorithms - AutoSet

ResMed’s AutoSet algorithm continually monitors each patient’s unique breathing pattern on a breath-by-breath basis – every hour, every night.

When AutoSet detects an event, it doesn’t just apply a fixed pressure response. Instead, AutoSet assesses the severity of each event – whether it is flow limitation, snoring or an apnea – before determining and delivering the ideal, lowest pressure solution to treat the event.

Once the event is treated and the patient’s breathing stabilizes, AutoSet gradually decreases the pressure, while continuously monitoring for recurring events. Patients remain comfortable through it all, and receive the therapy pressure that is just right for treating their OSA – no more and no less.

AutoSet Technology graph.png

Study of a Novel APAP Algorithm for the Treatment of Obstructive Sleep Apnea in Women

ResMed Corporation has recently developed a female-specific AutoSet for Her (AfH) algorithm; designed to optimize the pressure response to the specific patterns of obstructive sleep disordered breathing seen in women. The AfH algorithm is adapted from the S9 AutoSet algorithm (ResMed Ltd., Bella Vista, Sydney) with a number of modifications, including

  1. an increased sensitivity to flow limitation,
    • The AfH algorithm has been designed to be more sensitive to flow limitation by responding to the first identified flow-limited breath rather than requiring three consecutive flow-limited breaths, as occurs with the standard AutoSet algorithm.
  2. an optimized internal gain (a slower, and lower, pressure rise and decay in response to flow limitation),
    • the AfH algorithm increases pressure in response to flow limitation at a slower rate and to a lesser extent than the standard AutoSet algorithm (similarly the decay in the gain is lower).
  3. a lower cap on the pressure response to obstructive apneas,
    • In order to prevent an excessive pressure rise, the AfH algorithm does not increase pressure above 12 cm H2O in response to detected apneas (but pressure can increase above 12 cm H2O if other respiratory events are present).
  4. an adaptive minimum pressure
    • Another novel feature of the AfH algorithm is a moving minimum AutoSet pressure (i.e., a minimum pressure is set to which pressure decreases during sleep periods devoid of respiratory events). If apneas occur within a short time period the minimum AfH pressure will automatically increase and the pressure will not decline below this level for the remainder of the night’s therapy. The purpose of this is to minimize inappropriate pressure decreases during REM sleep that could occur with the standard AutoSet algorithm.



Conclusion: Among premenopausal women a novel female-specific autotitrating algorithm (AfH) is as effective as the standard AutoSet algorithm in controlling obstructive sleep apnea (OSA). The new algorithm may reduce flow limitation more than the standard algorithm and achieve control of OSA at a lower (95th centile) pressure.

Comparison of efficacy outcomes during standard AutoSet vs AutoSet for Her (AfH) treatment nights.

Efficacy Autoset vs AutosetForHer.PNG

The Full Paper (2015) File:AutoSetForHer-2015-aasm.38.11.1775.pdf

---Algorithms for Bilevel, ASV / SV, iVAPS / AVAPS---

This section is pending development. Sources Treatment of sleep-disordered breathing with positive airway pressure devices: technology update


The Link to the Original https://academic.oup.com/sleep/article-pdf/38/11/1775/13690051/aasm.38.11.1775.pdf


Philips Respironics

DreamStation

Auto CPAP algorithms

This was copied from Philips training slides

General behavior

The Auto algorithms are designed to keep upper airways open and provide optimal therapy pressure. Not only do they respond to obstructive events, they also proactively search for the lowest possible pressure needed by the patient.

When a patient experiences obstructive events such as apneas, hypopneas, flow limitations or vibratory snores, the DreamStation Auto algorithms increase pressure in response.

Analysis of the Flow will lead to the event being classified as obstructive or central and will generate the appropriate response.

When a pattern of obstructive events occur pressure increases to achieve airway patency.

If the device classifies the event as central pressure remains unchanged.

Flow Limitation

Flow Limitation is determined by evaluating 4 parameters of the patient's breathing - roundness, flatness, peak, and shape. If two of the four parameters fall out of trend it is considered a flow limitation. If a flow limitation is detected a high pressure search is initiated in which pressure is gradually increased. Note: BiPap devices respond with IPAP.

Vibratory Snore (VS)

During a vibratory snore pressure vibrations are detected.

If 3 vibratory snores are detected within 1 minute with less than 30 seconds between snores the algorithm increases pressure by 1cn over 15 seconds.

Note that for BiPAP devices these events will create a response for EPAP.

Apnea (obstructive or central)

An apnea is the absence or reduction of patient airflow by at least 80% for 10 seconds or more.

If 2 obstructive airway apneas/hypopneas are detected within 3 minutes the algorithm increases pressure by 1 cm.

Note BiPAP devices will create a response to obstructive events with EPAP. CPAP or BiPAP devices do not respond to central apneas.

Hypopnea (H)

A Hypopnea is the reduction of patient air flow by at least 40% for 10 seconds or more.

If 2 obstructive airway apneas/hypopneas are detected within 3 minutes the algorithm increases pressure by 1 cm. Note: BiPAP devices will create a response with IPAP.

Respiratory Effort Related Arousal (RERA)

A RERA is a sequence of breaths that exhibit both a subtle reduction in airflow during a 10 second period and a progressive increase in flow limitation. If a breath sequence is terminated by a sudden increase in air flow (along with the elimination of flow limitation a RERA is indicated.

If 2 RERA events are detected within 3 minutes pressure is increased by 0.5cm.

Periodic breathing

Periodic breathing such as Cheyne-Stokes Respiration (CSR) is defined as alternating periods of hyperventilation with waxing and wanning tidal volume and periods of central hypopneas and apneas.

No therapy adjustments are made in response to periodic breathing.




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